thasan@partners.org

Absorption of light leads to molecular excitation that can be exploited for therapy, treatment monitoring and diagnostics. The best known example of this is in medicine is Photodynamic therapy (PDT). The laboratory focuses on photophysical and biological mechanisms of PDT (such as singlet oxygen formation, cytokine secretion, etc) and exploiting this information for new combination strategies. In addition, programs are targeted on the development of therapies for diagnostic online monitoring of biological and chemical processes in the animal model and for targeted delivery of photoactivatable molecules to specific sites.