ScD in Chemical Engineering, Massachusetts Institute of Technology, 1974
BS in Chemical Engineering, Cornell University, 1970
Dr. Langer has received over 180 major awards including the 2006 United States National Medal of Science; the Charles Stark Draper Prize, considered the equivalent of the Nobel Prize for engineers and the 2008 Millennium Prize, the world’s largest technol
A major focus of Professor Langer's research is the study and development of polymers to deliver drugs, particularly genetically engineered proteins and DNA, continuously at controlled rates for prolonged periods of time. Work is in progress in the following areas:
Investigating the mechanism of release from polymeric delivery systems with concomitant microstructural analysis and mathematical modeling.
Studying applications of these systems including the development of effective long-term delivery systems for insulin, anti-cancer drugs, growth factors, gene therapy agents and vaccines.
Developing controlled release systems that can be magnetically, ultrasonically, or enzymatically triggered to increase release rates.
Synthesizing new biodegradable polymeric delivery systems which will ultimately be absorbed by the body.
Creating new approaches for delivering drugs such as proteins and genes across complex barriers in the body such as the blood-brain barrier, the intestine, the lung and the skin.
Shapiro MG, Westmeyer GG, Romero PA, Szablowski JO, Küster B, Shah A, Otey CR, Langer R, Arnold FH, Jasanoff A. Directed evolution of a magnetic resonance imaging contrast agent for noninvasive imaging of dopamine. Nat Biotechnol. 2010 Mar;28(3):264-70.
Levenberg S, Ferreira LS, Chen-Konak L, Kraehenbuehl TP, Langer R. Isolation, differentiation and characterization of vascular cells derived from human embryonic stem cells. Nat Protoc. 2010;5(6):1115-26.
Cao Y, Langer R. Optimizing the delivery of cancer drugs that block angiogenesis. Sci Transl Med. 2010 Jan 20;2(15):15ps3.
77 Massachusetts Avenue, E25-519, Cambridge, MA 02139